Professor Dale Poulter

Professor C. Dale Poulter

Education

  • B.S., 1964, Louisiana State University (Cum Laude)
  • Ph.D., 1967, University of California at Berkeley, with W.G. Dauben
  • Postdoctoral, 1967-69, University of California at Los Angeles, with S. Winstein

Contact

Office: HEB 2274

Phone: 801.581.6685

Email:poulter@chem.utah.edu

Awards

  • Honorary Professor, University of Queensland, Brisbande, Australia, 2002-2004
  • Repligen Award, Biological Division, American Chemical Society, 2002
  • Wilsmore Fellow, Melbourne University, 2001
  • Rosenblatt Award, University of Utah, 1999
  • Arthur C. Cope Scholar Award, American Chemical Society, 1998
  • Governor's Medal for Science and Technology, 1995
  • National Institutes of Health Merit Award, 1995
  • Fellow, American Association for the Advancement of Science, 1994
  • Utah Award, American Chemical Society, 1992
  • Ernest Guenther Award, American Chemical Society, 1991
  • Distinguished Research Award, University of Utah, 1984
  • David P. Gardner Faculty Fellow, 1983
  • Alfred P. Sloan Fellow, 1975-79
  • NIH Career Development Awardee, 1975-80
  • NIH Postdoctoral Fellow, 1967-69
  • NIH Predoctoral Fellow, 1965-67
  • Omnicron Delta Kappa, 1964
  • Phi Lambda Upsilon, 1964
  • Phi Kappa Phi, 1964

Professional Positions

  • Distinguished Professor of Chemistry, University of Utah, 1996-present
  • Chair, Department of Chemistry, University of Utah, 1995-2000
  • John A. Widtsoe Professor of Chemistry, University of Utah, 1994-present
  • Research Professor, Department of Medicinal Chemistry, University of Utah, 1978-present
  • Adjunct Professor, Department of Biochemistry, University of Utah, 1986-present
  • Professor, Department of Chemistry, University of Utah, 1978-1994
  • Director, Interdepartmental Program in Biological Chemistry, 1990-1993
  • Associate Professor, Department of Chemistry, University of Utah, 1975-1978
  • Associate Research Professor, Department of Biopharmaceutical Sciences, University of Utah, 1975-1978
  • Assistant Professor, Department of Chemistry, University of Utah, 1969-1975
  • Assistant Research Professor, Department of Biopharmaceutical Sciences, University of Utah, 1971-1975
  • Chemist, Esso Research Laboratory, Baton Rouge, Louisiana, Summer 1964
  • Chemist, PPG Chemicals, Lake Charles, Louisiana, Summers, 1962, 1963

Professional Activities

  • NAS, Bio2010, Chemistry sub-committee, 2001
  • AAAS, Member-at-Large, 2001-present
  • CS, Advisory Committee on Graduate Education, 2000-present
  • ACS, Committee on Professional Training, 1996-present
  • ACS, Councilor, Biological Division, 1993-present
  • AAAS, Nominating Committee Chemistry Division, 1997-1999, Chair 1999
  • ACS, Chair of Organic Division, 1998
  • ACS, Selection Committee; Editor of Organic Letters, 1998
  • ACS, Committee on Science, 1996-1999
  • NSF, Workshop on Organic Synthesis and Natural Products, co-organizer, 1993-1995
  • 14th Enzyme Mechanisms Conference, Scottsdale, AZ, Chair, 1993-95
  • 13th Enzyme Mechanisms Conference, Key Largo, FL, organizing committee, 1991-97
  • NIH, General Medical Sciences Council, 1990
  • ACS, American Coordinator, Biological Program, Pacific Basin Chemical Congress, 1989, 1995
  • PRF, Advisory Board, 1988-1990
  • ACS, Selection Committee; Editor of Journal of Organic Chemistry, 1988
  • ACS, Program Chairman for Biological Division, 1987
  • ACS, Canvassing Committee, Roger Adams Award in Organic Chemistry, 1986-1990
  • Gordon Conference on Enzymes, Coenzymes, and Metabolic Pathways, Chair, 1985
  • ACS, Executive Committee Organic Division, 1983-1986
  • NAS, Workshop on Effort Reporting Requirements of OMB Circular A-21; 1983
  • NIH, Ad Hoc member and Special Study Sections; 1980-1993
  • 7th Enzyme Mechanisms Conference; Sanibel, Florida; organizing committee, 1981-1983
  • ACS, Ad Hoc Task Force to monitor the Journal of Organic Chemistry; 1980-1981
  • NIH, Medicinal Chemistry A Study Section; 1977-81

Editorial Activities

  • Editor-in-Chief, Journal of Organic Chemistry, 2001- present
  • Senior Editor, Journal of Organic Chemistry, 2000-2001
  • Associate Editor, Organic Letters, 1999-2001
  • Associate Editor, Journal of Organic Chemistry, 1990-1995
  • Editorial Advisory Board, Chemical Reviews, 1996-2001
  • Editorial Advisory Board, Bioorganic & Medicinal Chemistry, 1993-present
  • Editorial Advisory Board, Journal of Organic Chemistry, 1987-1990
  • Editorial Board, Journal of Bioorganic Chemistry, 1983-1990
  • Editorial Advisory Board, Journal of the American Chemical Society, 1983-1986

Publications


  • Dauben, W.G.; Poulter, C.D. "The Addition of Methanol to Some Bicyclobutanes." Tetrahedron Lett., 1967, 3021-3025.
  • Dauben, W.G.; Poulter, C.D. "The Solvolysis of 1-Chlorobicyclo[3.3.1]nonane." J. Org. Chem., 1968, 33, 1237-1239.
  • Poulter, C.D.; Winstein, S. "The Cyclopropylcarbinyl-Allyl Rearrangement of a Hexamethyl-cyclopropylcarbinyl System." J. Am. Chem. Soc., 1969, 91, 3649-3650.
  • Poulter, C.D.; Winstein, S. "Solvolysis and Degenerate Cyclopropylcarbinyl-Cyclopropyl-carbinyl Rearrangement of a Hexamethylcyclopropylcarbinyl System." J. Am. Chem. Soc., 1969, 91, 3650-3652.
  • Poulter, C.D.; Friedrich, E.C.; Winstein, S. "The Stereochemistry of the Methylene Iodide-Zinc-Copper Couple Methylenation of Cyclic Allylic Alcohols." J. Am. Chem. Soc., 1969, 91, 6892-6894.
  • Poulter, C.D.; Friedrich, E.C.; Winstein, S. "Stereospecific Cationic Rearrangements of syn- and anti-Bicyclo[6.1.0]nonane Derivatives." J. Am. Chem. Soc., 1970, 92, 4274-4281.
  • Poulter, C.D.; Winstein, S. "Stereospecific Homoallylic Ring Expansions and Contractions." J. Am. Chem. Soc., 1970, 92, 4282-4288.
  • Dauben, W.G.; Poulter, C.D.; Suter, C. "Photoisomerizations of cis- and trans-3-Methylene-cyclodecene." J. Am. Chem. Soc., 1970, 92, 7408-7412.
  • Rilling, H.C.; Poulter, C.D.; Epstein, W.W.; Larsen, B. "Studies on the Mechanism of Squalene Biosynthesis. Presqualene Pyrophosphate, Stereochemistry and a Mechanism for Its Conver-sion to Squalene." J. Am. Chem. Soc., 1971, 93, 1783-1785.
  • Poulter, C.D.; Dickson, R.B. "Stereospecific 5J1H-1H and 6J1H-1H Couplings in 3-Methyl-3-azabicyclo [3.1.0]hexan-2,4-dione." Tetrahedron Lett., 1971, 2255-2258.
  • Poulter, C.D.; Boikess, R.S.; Brauman, J.I.; Winstein, S. "Shielding Effects of a Cyclopropane Ring." J. Am. Chem. Soc., 1972, 94, 2291-2296.
  • Poulter, C.D.; Winstein, S. "The a ,a ,2,2,3,3-Hexamethylcyclopropylcarbinyl System. A Study of Carbonium Ion Behavior in Nucleophilic and Superacid Solvents." J. Am. Chem. Soc., 1972, 94, 2297-2305.
  • Poulter, C.D.; Moesinger, S.G.; Epstein, W.W. "Solvolysis of N-Methyl-4-(chrysanthemyloxy) pyridinium Iodide--A Model for Non-Head-to-Tail Monoterpene Biosynthesis." Tetrahedron Lett., 1972, 67-70.
  • Poulter, C.D.; Goodfellow, R.J.; Epstein, W.W. "The Absolute Configuration of Santolina Alcohol from Ormenis multicaulis." Tetrahedron Lett., 1972, 71-74.
  • Poulter, C.D. "Model Studies of Terpene Biosynthesis. Stereoselective Ionization of N-Methyl-4-[(a S,1R,3R)-chrysanthemyloxy]pyridinium-d1 Iodide." J. Am. Chem. Soc., 1972, 94, 5515-5516.
  • Poulter, C.D.; Muscio, O.J.; Spillner, C.J.; Goodfellow, R.J. "Model Studies of Terpene Biosynthesis. Cationic Rearrangements Leading to Head-to-Head Terpenes." J. Am. Chem. Soc., 1972, 94, 5921-5923.
  • Poulter, C.D.; Anderson, R.B. "Direct Observation of Uracil Dication and Related Derivatives." Tetrahedron Lett., 1972, 3823-3826.
  • Epstein, W.W.; Poulter, C.D. "A Survey of Some Irregular Monoterpenes and their Biogenetic Analogies to Presqualene Alcohol." Phytochemistry, 1973, 12, 737-747.
  • Poulter, C.D. "Model Studies in Terpene Biosynthesis." Agric. and Food Chem., 1974, 22, 167-173.
  • Poulter, C.D.; Muscio, O.J.; Goodfellow, R.J. "Biosynthesis of Head-to-Head Terpenes. Carbonium Ion Rearrangements Which Lead to Head-to-Head Terpenes." Biochemistry, 1974, 13, 1530-1538.
  • Muscio, O.J.; Poulter, C.D. "Model Studies in Terpene Biosynthesis. Synthesis and Absolute Configuration of (+)-trans-2,2-Dimethyl-3-(2'-methyl-propenyl)cyclobutanol." J. Org. Chem., 1974, 39, 3288-3291.
  • Poulter, C.D.; Spillner, C.J. "The (trans-2'-Methylcyclopropyl)methyl System. Stereochemistry of Ionization, Rearrangement, and Solvent Capture." J. Am. Chem. Soc., 1974, 96, 7591-7593.
  • Poulter, C.D.; Muscio, O.J.; Goodfellow, R.J. "Model Studies of Terpene Biosynthesis. Synthesis of (+)-2-[trans-2'-(2'-Methylpropenyl)cyclopropyl]propan-2-ol." J. Org. Chem., 1975, 40, 139-140.
  • Frederick, G.D.; Poulter, C.D. "Extension of the HA Acidity Function into Oleum Mixtures." J. Am. Chem. Soc., 1975, 97, 1797-1801.
  • Poulter, C.D.; Frederick, G.D. "Uracil and its 4-Hydroxy-1(H) and 2-Hydroxy-3(H) Protomers. pKa's and Equilibrium Constants." Tetrahedron Lett., 1975, 2171-2174.
  • Spicer, L.D.; Poulter, C.D. "Isotopes as Probes for Determining Reaction Mechanisms." In Physical Chemistry. An Advanced Treatise; Vol. 7, H. Eyring, D. Henderson, W. Jost, Ed.; Academic Press: 1975.
  • Epstein, W.W.; McGee, L.R.; Poulter, C.D.; Marsh, L.L. "Mass Spectral Data for Gas Chromatograph--Mass Spectral Identification of Some Irregular Monoterpenes." J. Chem. and Engr. Data, 1976, 21, 500-502.
  • Poulter, C.D.; Rilling, H.C. "Prenyltransferase. The Mechanism of the Reaction." Biochemistry, 1976, 15, 1079-1083.
  • Poulter, C.D.; Satterwhite, D.M.; Rilling, H.C. "Prenyltransferase. The Mechanism of the Reaction." J. Am. Chem. Soc., 1976, 98, 3376-3377.
  • Poulter, C.D.; Argyle, J.C.; Mash, E.A. "Prenyltransferase. New Evidence for an Ionization-Condensation-Elimination Mechanism with 2-Fluorogeranyl Pyrophos-phate." J. Am. Chem. Soc., 1977, 99, 957-959.
  • Poulter, C.D.; Marsh, L.L.; Hughes, J.M.; Argyle, J.C.; Satterwhite, D.M.; Goodfellow, R.J.; Moesinger, S.G. "Model Studies of the Biosynthesis of Non-Head-to-Tail Terpenes. Rear-rangements of the Chrysanthemyl System." J. Am. Chem. Soc., 1977, 99, 3816-3823.
  • Poulter, C.D.; Hughes, J.M. "Model Studies of the Biosynthesis of Non-Head-to-Tail Terpenes. Stereochemistry of Ionization for N-Methyl-4-[(1S,1'R,3'R)-[1-2H]Chrysanthemyloxy]pyridinium Iodide." J. Am. Chem. Soc., 1977, 99, 3824-3829.
  • Poulter, C.D.; Hughes, J.M. "Model Studies of the Biosynthesis of Non-Head-to-Tail Terpenes. Stereochemistry of the Head-to-Head Rearrangement." J. Am. Chem. Soc., 1977, 99, 3830-3837.
  • Roberts, J.L.; Borromeo, P.S.; Poulter, C.D. "Addition of Grignard and Lithium Reagents to Eschenmoser's Salt. A Convenient Synthesis of Terminal Olefins." Tetrahedron Lett., 1977, 1299-1302.
  • Roberts, J.L.; Borromeo, P.S.; Poulter, C.D. "Addition of Eschenmoser's Salt to Ketone, Ester, and Lactone Enolates. A Convenient Synthesis of a -Methylene Carbonyls via Mannich Intermediates." Tetrahedron Lett., 1977, 1621-1624.
  • Poulter, C.D.; Satterwhite, D.M. "Mechanism of the Prenyl Transfer Reaction. Studies with (E)- and (Z)-3-Trifluoromethyl-2-buten-1-yl Pyrophosphate." Biochemistry, 1977, 16, 5470-5478.
  • Roberts, J.L.; Poulter, C.D. "2',3',5'-Tri-O-benzoyl[4-13C]uridine. An Efficient, Regiospecific Synthesis of the Pyrimidine Ring." J. Org. Chem., 1978, 43, 1547-1550.
  • Teranishi, R.; Flath, R.A.; Mon, T.R.; Poulter, C.D.; Kikuchi, M. "Volatile Constituents of California Sage Brush." Fragrance J., 1978, 6, 45-47.
  • Poulter, C.D.; Argyle, J.C.; Mash, E.A. "Farnesyl Pyrophosphate Synthetase. Mechanistic Studies of the 1'-4 Coupling Reaction with 2-Fluorogeranyl Pyrophosphate." J. Biol. Chem., 1978, 253, 7227-7233.
  • Poulter, C.D.; Rilling, H.C. "The Prenyl Transfer Reaction. Enzymatic and Mechanistic Studies of the 1'-4 Coupling Reaction in the Terpene Biosynthetic Pathway." Acc. Chem. Res., 1978, 11, 307-313.
  • Poulter, C.D.; Livingston, C.L. "[3-15N]-2',3',5'-Tri-O-benzoyluridine. Detection of Hydrogen Bonding in A-U Base Pairs by 15N NMR." Tetrahedron Lett., 1979, 755-758.
  • Gaughan, R.G.; Poulter, C.D. "Non-Head-to-Tail Monoterpenes. Synthesis of (S)-Lyratol and (S)-Lyratyl Acetate from (1R,3R)-Chrysanthemic Acid." J. Org. Chem., 1979, 44, 2441-2444.
  • Laskovics, F.M.; Krafcik, J.M.; Poulter, C.D. "Prenyltransferase. Kinetic Studies of the 1'-4 Coupling Reaction with Avian Liver Enzyme." J. Biol. Chem., 1979, 254, 9458-9463.
  • Poulter, C.D.; Mash, E.A.; Argyle, J.C.; Muscio, O.J.; Rilling, H.C. "Farnesyl Pyrophosphate Synthetase. Mechanistic Studies of the 1'-4 Coupling Reaction in the Terpene Biosynthetic Pathway." J. Am. Chem. Soc., 1979, 101, 6761-6763.
  • Laskovics, F.M.; Poulter, C.D. "Prenyltransferase. Determination of the Binding Mechanism and Individual Kinetic Constants for Farnesylpyrophosphate Synthetase by Rapid Quench and Isotope Partitioning Experiments." Biochemistry, 1981, 20, 1893-1901.
  • Poulter, C.D.; Wiggins, P.L.; Plummer, T.L. "Synthesis of Fluorinated Analogues of Geraniol." J. Org. Chem., 1981, 46, 1532-1538.
  • Dixit, V.M.; Laskovics, F.M.; Noall, W.I.; Poulter, C.D. "Tris-(tetra-n-butylammonium) Hydrogen Pyrophosphate. A New Reagent for the Preparation of Allylic Pyrophosphate Esters." J. Org. Chem., 1981, 46, 1967-1969.
  • Poulter, C.D.; Rilling, H.C. "Prenyl Transferases and Isomerase." In Biosynthesis of Isoprenoid Compounds; Volume 1, Chapter 4, J.W. Porter, Ed.; John Wiley & Sons: New York, 1981, pp. 162-224.
  • Poulter, C.D.; Rilling, H.C. "Conversion of Farnesyl Pyrophosphate to Squalene." In Biosynthesis of Isoprenoid Compounds; Volume 1, Chapter 8, J.W. Porter, Ed.; John Wiley & Sons: New York, 1981, pp. 414-441.
  • Poulter, C.D.; Argyle, J.C.; Mash, E.A.; Laskovics, G.M.; Wiggins, P.L.; King, C.R. "Inhibitors of Isoprenoid Biosynthesis." In Regulation of Insect Development and Behavior; Chapter 3, "Chemistry and Biochemistry of Juvenile Hormones", Wroclaw Technical University Press:, 1981, pp. 149-162.
  • Poulter, C.D.; Wiggins, P.L.; Le, A.T. "Farnesyl Pyrophosphate Synthetase. A Stepwise Mechanism for the 1'-4 Condensation Reaction." J. Am. Chem. Soc., 1981, 103, 3926-3927.
  • Mash, E.A.; Gurria, G.M.; Poulter, C.D. "Farnesyl Pyrophosphate Synthetase. Evidence for a Rigid Geranyl Cation-Pyrophosphate Anion Pair." J. Am. Chem. Soc., 1981, 103, 3927-3929.
  • King, C.-H.R.; Poulter, C.D. "Model Studies of Terpene Biosynthesis. Intermolecular 1'-2 Electrophilic Condensation of 3-Methyl-2-butenyl Acetate." J. Am. Chem. Soc., 1982, 104, 1413-1420.
  • Poulter, C.D.; King, C.-H.R. "Model Studies of Terpene Biosynthesis. Stereospecific Cyclization of N-Methyl-(S)-4-([1'-2H]neryloxy)pyridinium Methyl Sulfate to a -Terpineol." J. Am. Chem. Soc., 1982, 104, 1420-1422.
  • Poulter, C.D.; King, C.-H.R. "Model Studies of Terpene Biosynthesis. A Stepwise Mechanism for Cyclization of Nerol to a -Terpineol." J. Am. Chem. Soc., 1982, 104, 1422-1424.
  • Griffey, R.H.; Poulter, C.D.; Yamaizumi, Z.; Nishimura, S.; Hurd, R.E. "1H NMR Studies of 15N-Labeled Escherichia coli tRNAet. Use of 1J1H-15N Couplings to Identify Imino Resonances of Uridine-Related Bases." J. Am. Chem. Soc., 1982, 104, 5810-5811.
  • Griffey, R.H.; Poulter, C.D.; Yamaizumi, Z.; Nishimura, S.; Hurd, R.E. "1H NMR Studies of 15N-Labeled Escherichia coli tRNAet. An Unambiguous Assignment for the G-U Pair and Detection of a Uridine Resonance at 11.4 ppm." J. Am. Chem. Soc., 1982, 104, 5811-5813.
  • Sandifer, R.M.; Thompson, M.D.; Gaughan, R.G.; Poulter, C.D. "Squalene Synthetase. Inhibition by an Ammonium Analogue of a Carbocationic Intermediate in the Conversion of Presqualene Pyrophosphate to Squalene." J. Am. Chem. Soc., 1982, 104, 7376-7378.
  • Griffey, R.H.; Poulter, C.D.; Yamaizumi, Z.; Nishimura, S.; Hawkins, B.L. "1H NMR Studies of Nitrogen-15-Labeled Escherichia coli tRNAet. Assignments of Imino Resonances for Uridine-Related Bases by 1H-15N Heteronuclear Double Resonance Difference Spectroscopy." J. Am. Chem. Soc., 1983, 105, 143-145.
  • Griffey, R.H.; Poulter, C.D. "Efficient Syntheses of [3-15N]Uracil and [3-15N]Thymine." Nucleic Acids Research, 1983, 11, 6497-6504.
  • Griffey, R.H.; Poulter, C.D.; Bax, A.; Hawkins, B.L.; Yamaizumi, Z.; Nishimura, S. "Multiple Quantum Two-Dimensional 1H-15N Nuclear Magnetic Resonance Spectroscopy: Chemical Shift Correlation Maps for Exchangeable Imino Protons of Escherichia coli tRNAet in Water." Proc. Natl. Acad. Sci., 1983, 80, 5895-5897.
  • Griffey, R.H.; Poulter, C.D. "Detection of the Imino Hydrogen Bond in G-C Pairs by 1H and 15N Nuclear Magnetic Resonance Spectroscopy." Tetrahedron Lett., 1983, 24, 4067-4070.
  • Yang, T.-H.; Zabriskie, T.M.; Poulter, C.D. "Investigation of Isoprenoid Benzoates and Naphthoates by Reversed-Phase Liquid Chromatography. Isocratic Elution Characteristics of Benzoates and Naphthoates of C5-C20 Terpenoid Alcohols." J. Chromatography, 1984, 312, 121-132.
  • Capson, T.L.; Poulter, C.D. "A Facile Synthesis of Primary Amines from Carboxylic Acids by the Curtius Rearrangement." Tetrahedron Lett., 1984, 25, 3515-3518.
  • Dixit, V.M.; Poulter, C.D. "Convenient Syntheses of Adenosine 5'-Diphosphate, Adenosine 5'-Methylenediphosphonate, and Adenosine 5'-Triphosphate." Tetrahedron Lett., 1984, 25, 4055-4058.
  • Sagami, H.; Ogura, K.; Weiner, A.; Poulter, C.D. "Effect of Zinc Ions on Farnesyl Pyrophos-phate Synthetase Activity." Biochemistry Intl., 1984, 8, 661-667.
  • Davisson, V.J.; Woodside, A.B.; Poulter, C.D. "Synthesis of Allylic and Homoallylic Isoprenoid Pyrophosphates." Meth. Enzymol., 1985, 110, 130-144.
  • Bartlett, D.L.; King, C.-H.R.; Poulter, C.D. "Purification of Farnesyl Pyrophosphate Synthetase by Affinity Chromatography." Meth. Enzymol., 1985, 110, 171-184.
  • Yang, T.-H.; Zabriskie, T.M.; Poulter, C.D. "Reversed-Phase High Pressure Liquid Chromatography of C5 to C20 Isoprenoid Benzoates and Naphthoates." Meth. Enzymol., 1985, 111, 252-263.
  • Griffey, R.H.; Davis, D.; Yamaizumi, Z.; Bax, A.; Nishimura, S.; Hawkins, B.L.; Poulter, C.D. "15N Labeled E. coli tRNAet, tRNAGlu, tRNATyr, and tRNAPhe. Double Resonance and Two Dimensional NMR of H-N1 Units in Pseudouridine." J. Biol. Chem., 1985, 260, 9734-9741.
  • Davisson, V.J.; Neal, T.R.; Poulter, C.D. "Farnesyl Pyrophosphate Synthetase. A Case for Common Electrophilic Mechanisms for Prenyltransferases and Terpene Cyclases." J. Am. Chem. Soc., 1985, 107, 5277-5279.
  • Bartlett, D.L.; King, C.-H.R.; Poulter, C.D. "An Affinity Column for the Purification of Prenyltransferases." Anal. Biochem., 1985, 149, 507-515.
  • Heathcock, C.H.; Finkelstein, B.L.; Aoki, T.; Poulter, C.D. "Stereostructure of the Archaebacterial C40 Diol." Science, 1985, 229, 862-864.
  • Muehlbacher, M.; Poulter, C.D. "Isopentenyl Pyrophosphate: Dimethylallyl Pyrophosphate Isomerase. Irreversible Inhibition of the Enzyme by Active-Site Directed Covalent Attachment." J. Am. Chem. Soc., 1985, 107, 8307-8308.
  • Aoki, T.; Poulter, C.D. "Archaebacterial Isoprenoids. Synthesis of 2,3-Di-O-phytanyl-sn-glycerol and its 1,2-Isomer." J. Org. Chem., 1985, 50, 5634-5636.
  • Davis, D.R.; Griffey, R.H.; Yamaizumi, Z.; Nishimura, S.; Poulter, C.D. "15N Labeled tRNA. Identification of Dihydrouridine in E. coli tRNAet, tRNALys, and tRNAPhe by 1H-15N Two-Dimensional NMR." J. Biol. Chem., 1986, 261, 3584-3587.
  • Davisson, V.J.; Zabriskie, T.M.; Poulter, C.D. "Radiolabeled Allylic Isoprenoid Pyrophosphates: Synthesis, Purification, and Determination of Specific Activity." Bioorg. Chem., 1986, 14, 46-54.
  • Davisson, V.J.; Woodside, A.B.; Neal, T.R.; Stremler, K.E.; Muehlbacher, M.; Poulter, C.D. "Phosphorylation of Isoprenoid Alcohols." J. Org. Chem., 1986, 51, 4768-4779.
  • Griffey, R.H.; Davis, D.R.; Yamaizumi, Z.; Nishimura, S.; Hawkins, B.L.; Poulter, C.D. "15N Labeled tRNA. Identification of 4-Thiouridine in Escherichia coli tRNAer and tRNAyr by 1H-15N Two-Dimensional NMR Spectroscopy." J. Biol. Chem., 1986, 261, 12074-12078.
  • Davisson, V.J.; Davis, D.R.; Dixit, V.M.; Poulter, C.D. "Synthesis of Nucleotide 5'-Diphosphates from 5'-O-Tosyl Nucleosides." J. Org. Chem., 1987, 52, 1794-1801.
  • McClard, R.W.; Fujita, T.S.; Stremler, K.E.; Poulter, C.D. "Novel Phosphonylphosphinyl (P-C-P-C-) Analogs of Biochemically Interesting Diphosphates. Synthesis and Properties of P-C-P-C- Analogs of Isopentenyl Diphosphate and Dimethylallyl Diphosphate." J. Am. Chem. Soc., 1987, 109, 5544-5545.
  • Stremler, K.E.; Poulter, C.D. "Methane and Difluoromethanediphosphonate Analogs of Geranyl Diphsophate: Hydrolysis-Inert Alternate Substrates." J. Am. Chem. Soc., 1987, 109, 5542-5544.
  • Woodside, A.B.; Huang, Z.; Poulter, C.D. "Geranyl Diphosphate." Org. Syn., 1987, 66, 211-219.
  • Davisson, V.J.; Sharp, T.R.; Poulter, C.D. "Negative Ion Fast Atom Bombardment Mass Spectrometry of Isoprenoid Diphosphates and Related Analogs." Bioorg. Chem., 1988, 16, 111-123.
  • Muehlbacher, M.; Poulter, C.D. "Regioselective Opening of Simple Epoxides with Diisopropyl- amine Trihydrofluoride." J. Org. Chem., 1988, 53, 1026-1030.
  • Gmeiner, W.H.; Poulter, C.D. "An Efficient Synthesis of [8-13C]Adenine." J. Org. Chem., 1988, 53, 1322-1323.
  • Poulter, C.D.; Aoki, T.; Daniels, L. "Biosynthesis of Isoprenoid Membranes in the Methano-genic Archaebacterium Methanospirillum hungatei." J. Am. Chem. Soc., 1988, 110, 2620-2624.
  • Huang, Z.; Poulter, C.D.; Wolf, F.F.; Somers, T.C.; White, J.D. "Braunicene. A Novel Cyclic C32 Isoprenoid from Botryococcus braunii." J. Am. Chem. Soc., 1988, 110, 3959-3964.
  • Huang, Z.; Poulter, C.D. "Braunicene. Absolute Stereochemistry of the Cyclohexane Ring." J. Org. Chem., 1988, 53, 4089-4094.
  • Muehlbacher, M.; Poulter, C.D. "Isopentenyl-Diphosphate Isomerase. Inactivation of the Enzyme with Active-Site-Directed Inhibitors and Transition State Analogs." Biochemistry, 1988, 27, 7315-7328.
  • Gmeiner, W.H.; Poulter, C.D. "NMR Studies of Nucleic Acids. Deuterium Isotope Effects of 13C Chemical Shifts in Hydrogen Bonded Complexes of Pyrimidines and Purines." J. Am. Chem. Soc., 1988, 110, 7640-7647.
  • Huang, Z.; Poulter, C.D. "Isobraunicene, Wolficene, and Isowolficene. New Cyclic 1'-3 Fused Isoprenoids from Botryococcus braunii." J. Org. Chem., 1988, 53, 5390-5392.
  • Capson, T.L.; Thompson, M.D.; Dixit, V.M.; Gaughan, R.G.; Poulter, C.D. "Synthesis of Ammonium Analogs of Carbocationic Intermediates in the Conversion of Presqualene Diphosphate to Squalene." J. Org. Chem., 1988, 53, 5903-5908.
  • Huang, Z.; Poulter, C.D. "Stereochemical Studies of Botryococcene Biosynthesis: Analogies between 1'-1 and 1'-3 Condensation in the Isoprenoid Pathway." J. Am. Chem. Soc., 1989, 111, 2713-2715.
  • Davis, D.R.; Yamaizumi, Z.; Nishimura, S.; Poulter, C.D. "15N Labeled 5S RNA. Identification of Uridine Base Pairs in E. coli 5S RNA by 1H-15N Multiple Quantum NMR." Biochemistry, 1989, 28, 4105-4108.
  • Poulter, C.D.; Capson, T.L.; Thompson, M.D.; Bard, R.M. "Squalene Synthetase. Inhibition by Ammonium Analogs of Carbocationic Intermediates in the Conversion of Presqualene Diphosphate to Squalene." J. Am. Chem. Soc., 1989, 111, 3734-3739.
  • Poulter, C.D.; Muehlbacher, M.; Davis, D.R. "Isopentenyl Diphosphate Isomerase. Mechanism of Active-Site-Directed Irreversible Inhibition by 3-(Fluoromethyl)-3-butenyl Diphosphate." J. Am. Chem. Soc., 1989, 111, 3740-3742.
  • Huang, Z.; Poulter, C.D. "Tetramethylsqualene. A New Triterpene from Botryococcus braunii var. Showa." Phytochemistry, 1989, 28, 1467-1470.
  • Sherman, M.M.; Petersen, L.; Poulter, C.D. "Isolation and Characterization of Isoprene Mutants of Escherichia coli." J. Bacteriology, 1989, 171, 3619-3628.
  • Anderson, M.S.; Muehlbacher, M.; Street, I.P.; Proffitt, J.; Poulter, C.D. "Isopentenyl-Diphosphate:Dimethylallyl-Diphosphate Isomerase. An Improved Purification of the Enzyme and Isolation of the Gene from Saccharoymces cerevisiae." J. Biol. Chem., 1989, 264, 19169-19175.
  • Anderson, M.S.; Yarger, J.G.; Burck, C.L.; Poulter, C.D. "Farnesyl Diphosphate Synthetase. Molecular Cloning, Sequence, and Expression of an Essential Gene from Saccharomyces cerevisiae." J. Biol. Chem., 1989, 264, 19176-19184.
  • Huang, Z.; Poulter, C.D. "Isoshowacene. A New C31 Hydrocarbon from Botryococcus braunii var. Showa." Phytochemistry, 1989, 28, 3043-3046.
  • Mautz, D.; Davisson, V.J.; Poulter, C.D. "Synthesis of O-Geranyl (1-Thio)diphosphate." Tetrahedron Lett., 1989, 30, 7333-7336.
  • Poulter, C.D. "Isopentenyl Diphosphate to Squalene. Enzymology and Inhibition." In The Biochemistry of Cell Walls and Membranes in Fungi; Chapter 12, P.J. Kuhn, A.P.J. Trinci, M.J. Jung, M.W. Goosey, L.G. Copping, Eds.; Springer-Verlag: Berlin, 1990, 169-188.
  • Zhang, D.L.; Daniels, L.; Poulter, C.D. "Biosynthesis of Archaebacterial Membranes. Formation of Isoprene Ethers by a Prenyl Transfer Reaction." J. Am. Chem. Soc., 1990, 112, 1264-1265.
  • Poulter, C.D. "Biosynthesis of Non-Head-to-Tail Terpenes. Formation of 1'-1 and 1'-3 Linkages." Acc. Chem. Res., 1990, 23, 70-77.
  • Street, I.P.; Poulter, C.D. "Isopentenyldiphosphate:Dimethylallyldiphosphate Isomerase: Construction of a High-Level Heterologous Expression System for the Gene from Saccharomyces cerevisiae and Identification of an Active-Site Nucleophile." Biochemistry, 1990, 29, 7531-7538.
  • Schafer, W.R.; Trueblood, C.E.; Yang, C.-C.; Mayer, M.P.; Rosenberg,S.; Poulter, C.D.; Kim, S.-H.; Rine, J. "Enzymatic Coupling of Cholesterol Intermediates to a Mating Pheromone Precursor and to the Ras Protein." Science, 1990, 249, 1133-1139.
  • Street, I.P.; Christensen, D.J.; Poulter, C.D. "Hydrogen Exchange During the Enzyme Catalyzed Isomerization of Isopentenyl Diphosphate and Dimethylallyl Diphosphate." J. Am. Chem. Soc., 1990, 112, 8577-8578.
  • Brown, M.J.; Milano, P.D.; Lever, D.C.; Epstein, W.W.; Poulter, C.D. "Prenylated Proteins. A Convenient Synthesis of Farnesyl Cysteinyl Thioethers." J. Am. Chem. Soc., 1991, 113, 3176-3177.
  • Davis, D.; Poulter, C.D. "1H-15N NMR studies of E. coli tRNAPhe from HisT Mutants: A Structural Role for Pseudouridine." Biochemistry, 1991, 30, 4223-4231.
  • Ding, V.D.-H.; Sheares, B.T.; Bergstrom, J.D.; Ponpipom, M.M.; Perez, L.B.; Poulter, C.D. "Purification and Characterization of Recombinant Human Farnesyl Diphosphate Synthetase Expressed in E. coli." Biochem. J., 1991, 275, 61-65.
  • Poulter, C.D.; Mautz, D. "Solvolysis of Allylic Phosphorothioate Esters. A Mechanistic Study of the Thiono ® Thiolo Rearrangement." J. Am. Chem. Soc., 1991, 113, 4895-4903.
  • Street, I.P.; Coffman, H.R.; Poulter, C.D. "Isopentenyl Diphosphate Isomerase. Site-Directed Mutagenesis of Cys139 Using "Counter" PCR Amplification of an Expression Plasmid." Tetrahedron, 1991, 47, 5919-5924.
  • Gebler, J.C.; Poulter, C.D. "Purification and Characterization of Dimethylallyl Tryptophan Synthase from Claviceps purpurea." Arch. Biochem. Biophys., 1992, 296, 308-313.
  • Math, S.K.; Hearst, J.E.; Poulter, C.D. "The crtE Gene in Erwinia herbicola Encodes Geranyl-geranyl Diphosphate Synthase." Proc. Natl. Acad. Sci. USA, 1992, 89, 6761-6764.
  • Gebler, J.C.; Woodside, A.B.; Poulter, C.D. "Dimethylallyltryptophan Synthase. An Enzyme Catalyzed Electrophilic Aromatic Substitution." J. Am. Chem. Soc., 1992, 114, 7354-7360.
  • Mayer, M.P.; Hahn, F.M.; Stillman, D.J.; Poulter, C.D. "Disruption and Mapping of IDI1. The Gene for Isopentenyl Diphosphate Isomerase in Saccharomyces cerevisiae." Yeast, 1992, 8, 743-748.
  • Lu, X.J.; Christensen, D.J.; Poulter, C.D. "Isopentenyl Diphosphate Isomerase. Irreversible Inhibition by 3-Methyl-3,4-epoxybutyl Diphosphate." Biochemistry, 1992, 31, 9955-9960.
  • Marrero, P.F.; Poulter, C.D.; Edwards, P.A. "Effects of Site Directed Mutagenesis of the Highly Conserved Aspartate Residues in Domain II of Farnesyl Diphosphate Synthase Activity." J. Biol. Chem., 1992, 267, 21873-21878.
  • Davisson, V.J.; Neal, T.R.; Poulter, C.D. "Farnesyl Diphosphate Synthase. Catalysis of an Intramolecular Prenyl Transfer with Bisubstrate Analogs." J. Am. Chem. Soc., 1993, 115, 1235-1245.
  • Davisson, V.J.; Poulter, C.D. "Farnesyl Diphosphate Synthase. Interplay between Substrate Topology, Stereochemistry, and Regiochemistry in Electrophilic Alkylations." J. Am. Chem. Soc., 1993, 115, 1245-1260
  • Zhang, D.L.; Poulter, C.D. "Biosynthesis of Archaebacterial Ether Lipids. Formation of Ether Linkages by Prenyltransferases." J. Am. Chem. Soc., 1993, 115, 1270-1277.
  • Chen, A.-J.; Poulter, C.D. "Purification and Characterization of Farnesyl Diphosphate/ Geranylgeranyl Diphosphate Synthase. A Thermostable Bifunctional Enzyme from Methano-bacterium thermoautotrophicum." J. Biol. Chem., 1993, 268, 11002-11007.
  • Zhang, D.; Poulter, C.D. "Biosynthesis of Archaebacterial Lipids in Halobacterium halobium and Methanobacterium thermoautotrophicum." J. Org. Chem., 1993, 58, 3919-3922.
  • Zhang, D.; Jennings, S.M.; Robinson, G.W.; Poulter, C.D. "Yeast Squalene Synthase. Expression, Purification and Characterization of Soluble Recombinant Enzyme." Arch. Biochem. Biophys., 1993, 304, 133-143.
  • Zhang, D.; Poulter, C.D. "Analysis and Purification of Phosphorylated Isoprenoids by Reversed-Phase HPLC." Anal. Biochem., 1993, 213, 356-361.
  • Mayer, M.P.; Prestwich, G.D.; Dolence, J.M.; Bond, P.D.; Wu, H.-y.; Poulter, C.D. "Protein Farnesyltransferase. Expression and Immunoaffinity Purification of the Heterodimeric Protein from Saccharomyces cerevisiae." Gene, 1993, 132, 41-47.
  • Chen, A.; Zhang, D.; Poulter, C.D. "(S)-Geranylgeranylglyceryl Phosphate Synthase. Purification and Characterization of the First Pathway-Specific Enzyme in Archaebacterial Membrane Lipid Biosynthesis." J. Biol. Chem., 1993, 268, 21701-21705.
  • Mookhtiar, K.A.; Kalinowski, S.S.; Zhang, D.; Poulter, C.D. "Yeast Squalene Synthase. A Mechanism for Addition of Substrates and Activation by NADPH." J. Biol. Chem., 1994, 269, 11201-11207.
  • Song, L.; Poulter, C.D. "Yeast Farnesyl Diphosphate Synthase. Site-Directed Mutagenesis of Residues in Highly-Conserved Prenyltransferase Domains I and II." Proc. Natl. Acad. Sci. USA, 1994, 91, 3044-3048.
  • Street, I.P.; Coffman, H.R.; Baker, J.A.; Poulter, C.D. "Identification of Cys139 and Glu207 as Catalytically Important Groups in the Active Site of Isopentenyldiphosphate:Dimethyl-allyldiphosphate Isomerase." Biochemistry, 1994, 33, 4212-4217.
  • Chen, A.; Poulter, C.D. "Isolation and Characterization of idsA. The Gene for the Short Chain Isoprenyl Diphosphate Synthase from Methanobacterium thermoautotrophicum." Arch. Biochem. Biophys., 1994, 314, 399-404.
  • Poulter, C.D.; Dolence, J.M.; Bond, P.D. "Protein Farnesyltransferase: A Mechanism of Action." J. Protein Chem., 1994, 13, 488-489.
  • Tarshis, L.C.; Yan, M.; Poulter, C.D.; Sacchettini, J.C. "Crystal Structure of Recombinant Farnesyl Diphosphate Synthase at 2.6 Angstroms" Biochemistry, 1994, 33, 10871-10877.
  • Christensen, D.J.; Poulter, C.D. "Enzymatic Synthesis of Isotopically Labeled Isoprenoid Diphosphates." Bioorg. Med. Chem., 1994, 2, 631-637.
  • Chen, A.; Kroon, P.; Poulter, C.D. "Isoprenyl Diphosphate Synthases: Protein Sequence Comparisons, A Phylogenetic Tree, and Predictions of Secondary Structure." Protein Sci., 1994, 3, 600-607.
  • Cassidy, P.B.; Dolence, J.M.; Poulter, C.D. "Continuous Fluorescence Assay for Protein Prenyltransferases." In Methods in Enzymology; P.J. Casey, J.E. Buss, Eds.; Academic Press: San Diego, 1995, Vol. 250, pp. 30-43.
  • Zhang, D.; Poulter, C.D. "Biosynthesis of Non-Head-to-Tail Isoprenoids. Syntheses of 1'-1 and 1'-3 Structures by Recombinant Yeast Squalene Synthase." J. Am. Chem. Soc., 1995, 117, 1641-1642.
  • Rogers, D.H.; Yi, E.C.; Poulter, C.D. "An Enantioselective Synthesis of (+)-Presqualene Diphosphate." J. Org. Chem., 1995, 60, 941-945.
  • Hahn, F.M.; Poulter, C.D. "Isolation of Schizosaccharomyces pombe Isopentenyl Diphosphate Isomerase cDNA Clones by Complementation and Synthesis of the Enzymes in E. coli." J. Biol. Chem., 1995, 270, 11298-11303.
  • Dolence, J.M.; Poulter, C.D. "A Mechanism for Posttranslational Modification of Proteins by Yeast Protein Farnesyl Transferase." Proc. Natl. Acad. Sci., 1995, 92, 5008-5011.
  • Stirtan, W.G.; Poulter, C.D. "Yeast Protein Geranylgeranyltransferase Type-I: Overproduction, Purification and Characterization." Arch. Biochem. Biophys., 1995, 321, 182-190.
  • Doyle, M.P; Protopopova, M.N.; Poulter, C.D.; Rogers, D.H. "Macrocyclic Lactones from Dirhodium(II) Catalyzed Intramolecular Cyclopropanation and Carbon-Hydrogen Insertion." J. Am. Chem. Soc., 1995, 117, 7281-7282.
  • Jiang, Y.; Proteau, P.; Poulter, C.D.; Ferro-Novick, S. "BTS1 Encodes a Geranylgeranyl Diphosphate Synthase Saccharomyces cerevisiae." J. Biol. Chem., 1995, 270, 21793-21799.
  • Humpf, H.-U.; Berova, N.; Nakanishi, K.; Jarstfer, M.B.; Poulter, C.D. "Allylic and Homoallylic CD Exciton Chirality: A Sensitive Method for Determining the Absolute Stereochemistry of Natural Products." J. Org. Chem., 1995, 60, 3539-3542.
  • Gibbs, R.A.; Krishna, U.; Dolence, J.; Poulter, C.D. "A Stereoselective Palladium Copper-Catalyzed Route to Isoprenoids. Synthesis and Biological Evaluation of 13-Methylidenefarnesyl Diphosphate." J. Org. Chem., 1995, 60, 7821-7829.
  • Tsai, H.-F.; Wang, H.; Gebler, J.C.; Poulter, C.D.; Schardl, C.L. "The Claviceps purpurea Gene Encoding Dimethylallyltryptophan Synthase, the Committed Step for Ergot Alkaloid Biosynthesis." Biochem. Biophys. Res. Comm., 1995, 216, 119-125.
  • Dolence, J.M.; Cassidy, P.B.; Mathis, J.R.; Poulter, C.D. "Yeast Protein Farnesyl-transferase: Steady-State Kinetic Studies of Substrate Binding." Biochemistry, 1995, 34, 16687-16694.
  • Anderson-Altmann, K.L.; Phung, C.G.; Mavromoustakos, S.; Zheng, Z.; Facelli, J.C.; Poulter, C.D.; Grant, D.M. "The 15N Chemical Shift Tensors of Uracil Determined from 15N Powder Pattern and 15N-13C Dipolar NMR Spectroscopy." J. Phys. Chem., 1995, 99, 10454-10458.
  • Dolence, J.M.; Poulter, C.D. "Synthesis of Analogs of Farnesyl Diphosphate." Tetrahedron Symposium-in-Print,, 1996, 52, 119-130.
  • Hahn, F.M.; Baker, J.A.; Poulter, C.D. "Open Reading Frame 176 in the Photosynthesis Gene Cluster of Rhodobacter capsulatus Encodes idi, a Gene for Isopentenyl Diphosphate Isomerase." J. Bacteriol., 1996, 178, 619-624.
  • Moore, J.A.; Chen, A.; Mujing, Y.; Hurlburt, A.P.; Poulter, C.D. "Identification of the gltX Gene Encoding Glutamyl-tRNA Synthetase from Methanobacterium thermoautotrophicum." Biochim. Biophys. Acta, 1996, 1305, 113-116.
  • Biller, S.A.; Neuenschwander, K.; Ponpipom, M.M.; Poulter, C.D. "Squalene Synthase Inhibitors." Current Pharm. Design, 1996, 2, 1-40.
  • Hahn, F.M.; Xuan, J.W.; Chambers, A.F.; Poulter, C.D. "Human Isopentenyl Diphosphate:Dimethylallyl Diphosphate Isomerase: Overproduction, Purification and Characterization." Arch. Biochem. Biophys., 1996, 332, 30-34.
  • Witter, D.J.; Poulter, C.D. "Yeast Geranylgeranyltransferase Type-II: Steady State Kinetic Studies of the Recombinant Enzyme." Biochemistry, 1996, 35, 10454-10463.
  • Ratemi, E.S.; Dolence, J.M.; Poulter, C.D.; Vederas, J.C. "Synthesis of Protein Farnesyltransferase and Protein Geranylgeranyl-transferase Inhibitors: Rapid Access to Chaetomellic Acid A and Its Analogues." J. Org. Chem., 1996, 61, 6296-6301.
  • Cassidy, P.B.; Poulter, C.D. "Transition State Analogs for Protein Farnesyltransferase." J. Am. Chem. Soc., 1996, 118, 8761-8762.
  • Poulter, C.D. "Mechanistic Studies of the Prenyl Transfer Reaction with Fluorinated Substrate Analogs." In Biomedical Frontiers of Fluorine Chemistry; I. Ojima, J.R. McCarthy, J.T. Welch, Eds.; ACS Symposium Series 639, 1996, 158-168.
  • Mu, Y.-Q.; Gibbs, R.A.; Eubanks, L.M.; Poulter, C.D. "Cuprate-Mediated Synthesis and Biological Evaluation of Cyclopropyl and tert-Butyl Farnesyl Diphosphate Analogs." J. Org. Chem., 1996, 61, 8010-8015.
  • Tarshis, L.C.; Proteau, P.J.; Kellogg, B.A.; Sacchettini, J.C.; Poulter, C.D. "Regulation of Product Chain Length by Isoprenyl Diphosphate Synthases." Proc. Natl. Acad. Sci. USA, 1996, 93, 15018-15023.
  • Jarstfer, M.B.; Blagg, B.S.J.; Rogers, D.H.; Poulter, C.D. "Biosynthesis of Squalene. Evidence for a Tertiary Cyclopropylcarbinyl Cationic Intermediate in the Rearrangement of Presqualene Diphosphate to Squalene." J. Amer. Chem. Soc., 1996, 118, 13089-13090.
  • Moore, J.A.; Poulter, C.D. "Escherichia coli Dimethylallyl Diphosphate: tRNA Dimethylallyltransferase." Biochemistry, 1997, 36, 604-614.
  • Stirtan, W.G.; Poulter, C.D. "Yeast protein Geranylgeranyltransferase Type-I: Steady-state Kinetics and Substrate Binding." Biochemistry, 1997, 36, 4552-4557.
  • Mathis, J.R.; Poulter, C.D. "Yeast Protein Farnesyltransferase. A Presteady-State Kinetic Analysis." Biochemistry, 1997, 36, 6367-6376.
  • Mathis, J.R.; Back, K.; Starks, C.; Noel, J.; Poulter, C.D.; Chappell, J. "A Pre-Steady State Study of Recombinant Sesquiterpene Cyclases." Biochemistry, 1997, 36, 8340-8348.
  • Dolence, J.M.; Rozema, D.M.; Poulter, C.D. "Yeast Protein Farnesyltransferase. Site-Directed Mutagenesis of Conserved Residues in the b -Subunit." Biochemistry, 1997, 36, 9246-9252.
  • Sacchettini, J.C.; Poulter, C.D. "Creating Isoprenoid Diversity." Science, 1997, 277, 1788.
  • Campbell, M.; Hahn, F.M.; Poulter, C.D.; Leustek, T. "Analysis of the Isopentenyl Diphosphate Isomerase Gene Family from Arabidopsis thaliana." Plant Molec. Biol., 1997, 36, 323-328.
  • Kellogg, B.; Poulter, C.D. "Chain Elongation in the Isoprenoid Biosynthetic Pathway." Curr. Opin. Chem. Biol., 1997, 1, 570-578.
  • Poulter, D.; Goldenberg, D. "Structure: Organic biological molecules." In Principles of Chemistry in Biology; Theil, E.C., Ed.; Am. Chem. Soc.: Washington, DC, 1998, pp. 1-49.
  • Dolence, J.M.; Poulter, C.D. "Electrophilic Alkylations, Isomerizations, and Rearrangements." In Comprehensive Natural Products Chemistry; Meth-Cohn, O., Ed.; Elsevier: Oxford, 1998,Vol. 5, pp. 18473-18500.
  • Koohang, A.; Coates, R.M.; Owen, D.; Poulter, C.D. "Synthesis and Evaluation of Aziridine Analogs of Presqualene Diphosphate as Squalene Synthase Inhibitors," J. Org. Chem., 1999, 64, 6-7.
  • Blagg, B.S.J.; Poulter, C.D. "Synthesis of 1-Deoxy-D-xylulose and 1-Deoxy-D-xylulose-5-phosphate," J. Org. Chem., 1999, 64, 1508-1511.
  • Leyes, A.E.; Baker, J.A.; Hahn, F.M.; Poulter, C.D. "Biosynthesis of Isoprenoids in Escherichia coli: Stereochemistry of the Reaction Catalyzed by Isopentenyl Diphosphate:Dimethylallyl Diphosphate Isomerase," Chem. Comm., 1999, 717-718.
  • Hahn, F.M.; Hurlburt, A.P.; Poulter, C.D. "Escherichia coli Open Reading Frame 6961 is idi, a Non-Essential Gene Encoding Isopentenyl Diphosphate Isomerase," J. Bacteriology, 1999, 181, 4499-4504.
  • Wu, Z.; Demma, M.; Strickland, C.L.; Radisky, E.S.; Poulter, C.D.; Le, H.V.; Windsor, W.T. "Farnesyl Protein Transferase: Identification of K164a and Y300b as Catalytic Residues by Mutagenesis and Kinetic Studies", Biochemistry, 1999, 38, 11239-11249.
  • Rozema, D.B.; Phillips, S.T.; Poulter, C.D. " Yeast Protein Farnesyltransferase. Binding of S-Alkyl Peptides and Related Analogs", Org Lett, 1999, 1, 815-817.
  • Leyes, A.E.; Poulter, C.D. "Synthesis of (R)-[2-2H]isopentenyl Diphosphate and Determination of Its Enantiopurity by 2H NMR Spectroscopy in a Lyotropic Medium", Org Lett, 1999, 1, 1067-1070.
  • Leyes, A.E.; Baker, J.A.; Poulter, C.D. "Biosynthesis of Isoprenoids in E. coli: Stereochemistry of the Reaction Catalyzed by Farnesyl Diphosphate Synthase", Org Lett, 1999, 1, 1071-1073.
  • Rozema, D.B.; Poulter, C.D. "Yeast protein Farnesyltransferase. pKas of Peptide Substrates Bound as Zinc Thiolates" Biochemistry, 1999, 38, 13138-13146.
  • Koppisch, A.T.; Blagg, B.S.J.; Poulter, C.D. "Synthesis of 2-C-Methyl-D-erythritol-4-phosphate: The First Pathway Specific Intermediate in the Methylerythritol Phosphate Route to Isoprenoids", Org. Lett., 2000, 2, 215-217.
  • Radisky, E.S.; Poulter, C.D. "Squalene Synthase: Steady State, Pre-Steady State, and Isotope Trapping Studies", Biochemistry, 2000, 39, 1748-1760.
  • Dolence, J.M.; Steward, L.E.; Dolence, E.K.; Wong, D.H. Poulter, C.D. "Overproduction of the Yeast CaaX Prenyl Protease Rce1p in Saccharomyces cerevisiae and Its Initial Biochemical Characterization", Biochemistry, 2000, 39, 4096-4104.
  • Harris, C.M.; Poulter, C.D. "Recent Studies of the Mechanism of Protein Prenylation", Nat. Prod. Rept., 2000, 17, 131-214.
  • Soderberg, T.; Poulter, C.D. "Escherichia coli Dimethylallyl Diphosphate:tRNA Dimethylallyltransferase: Essential Elements for Recognition of tRNA Substrates Within the Anticodon Stem-Loop", Biochemistry,, 2000, 39, 6546-6553.
  • Trueblood, C.E.; Boyartchuk, V.L.; Picologlou, E.; Rozema, D.; Poulter, C.D.; Rine, J. "The CaaX Proteases, Afc1p and Rce1p, Have Overlapping but Distinct Substrate Specificities", Molec. Cell. Biol., 2000, 20.
  • Moore, J.A.; Mathis, J.R.; Poulter, C.D. "Escherichia coli Dimethylallyl Diphosphate: tRNA Dimethylallyltransferase: Presteady State Kinetic Studies," Biochim et Biophys Acta, 2000, 1479, 166-174.
  • Phan, R.M.; Poulter, C.D. "Synthesis of Geranyl S-thiolodiphosphate. A New Alternate Substrate/Inhibitor for Prenyltransferases", Org Lett, 2000, 2, 2287-2289.
  • Dolence, E.K.; Dolence, J.M.; Poulter, C.D. "Solid-Phase Synthesis of a Farnesylated CaaX Peptide Library: Inhibitors of the Ras CaaX Endoprotease", J. Comb. Chem, 2000 2,522-536.
  • Fernandez, S.M.; Kellogg, B.A.; Poulter, C.D. "Farnesyl Diphosphate Synthase. Altering the Catalytic Site to Select for Geranyl Diphosphate Activity", Biochemistry, 2000, 39, 15316-17.
  • Hahn, F.M.; Eubanks, L.M.; Blagg, B.S.J.; Testa, C.; Baker, J.A..; Poulter, C.D. "1-Deoxyxylulose-5-Phosphate Synthase: The Gene Product of both ORF 2816 and ORF 2895 in Rhodobacter capsulatus", J. Bacteriology, 2001, 183, 1-11.
  • Dunford, J.E.; Coxon, F.P.; Luckman, S.P.; Thompson, K.; Hahn, F.M.; Poulter, C.D.; Rogers, M.J. "Identification of FPP Synthase, the Molecular Target of Nitrogen-Containing Bisphosphonates, Using a Cell-Free Protein Prenyl Assay", J. Pharm. Exper. Therapeutics, 2001, 296, 235-242.
  • Dolence, E.K.; Dolence, J.M.; Poulter, C.D. "Solid-Phase Synthesis of a Radiolabeled, Biotinylated, and Farnesylated Ca1a2X Peptide Substratea for Ras- and a-Mating Factor Converting Enzyme", Bioconjugate Chem., 2001, 12, 35-43.
  • Soderberg, T.; Poulter, C.D. "Escherichia coli Dimethylallyl Diphosphate:tRNA Dimethylallyltransferase: Site-Directed Mutagenesis of Highly conserved Residues", Biochemistry, 2001, 40, 1734-1740.
  • Rivera, S.B.; Swedlund, B.D.; King, G.J.; Bell, R.N.; Hussey, Jr., C.E.; Shattuck-Eidens, D.M.; Wrobel, W.M.; Peiser, G.D.; Poulter, C.D. "Chrysanthemyl Diphosphate Synthase: Isolation of the Gene and Characterization of the Recombinant Non-Head-to-Tail Monoterpene Synthase from Chrysanthemum cinerariaefolium", Proc. Natl. Acad. Sci. US, 2001, 98, 4373-4378.
  • Phan, R.M.; Poulter, C.D. "Synthesis of (S)-Isoprenoid Thiodiphosphates as Substrates and Inhibitors", J. Org. Chem., 2001, 66, 6705-6710.
  • Soderberg, T.; Chen, A.; Poulter, C.D. "Geranylgeranylglyceryl Phosphate Synthase. Characterization of the Recombinant Enzyme from Methanobacterium thermoautotrophicum", Biochemistry, 2001, 40,14847-14854.
  • Mu, Y.Q.; Eubanks, L.M.; Poulter, C.D.; Gibbs, R.A. "Coupling of Isoprenoid Triflates with Organoboron Nucleophiles: Synthesis and Biological Evaluation of Geranylgeranyl Diphosphate Analogs" Bioorg. Med. Chem., 2002, 10, 1207-1219.
  • Koppish, A.T.; Fox, D.T.; Blagg, B.S.J.; Poulter C.D. "E. coli MEP Synthase: Steady-State Kinetic Analysis and Substrate Binding" Biochemistry, 2002, 41, 236-243.
  • Fox, D.T.; Poulter, C.D. "Synthesis of (E)-4-Hydroxydimethylallyl Diphosphate. An Intermediate in the Methyl Erythritol Phosphate Branch of the Isoprenoid Pathway" J. Org. Chem., 2002, 67, 5009-5010.
  • Jarsfter, M.B.; Zhang, D.L.; Poulter, C.D. "Recombinant Squalene Synthase. Synthesis of Non-Head-to-Tail Isoprenoids in the Absence of NADPH" J. Am. Chem. Soc., 2002, 124, 8834-8845.
  • Blagg, B.S.J.; Jarstfer, M.B.; Rogers, D.H., Poulter, C.D. "Recombinant Squalene Synthase. A Mechanism for the Rearrangement of Presqualene Diphosphate to Squalene" J. Am. Chem. Soc., 2002, 124, 8846-8853.
  • Koppish, A.T.; Poulter, C.D. "Synthesis of 4-Diphosphocytidyl-2-C-methyl-D-erythritol and 2-C-Methyl-D-erythritol 4-Phosphate" J. Org. Chem., 2002, 67, 5416-5418.
  • Harris, C.M.; Derdowski, A.M.; Poulter, C.D. "Modulation of the Zn(II) Center in Protein Farnesyltransferase by Mutagenesis of the Zn(II) Ligands", Biochemistry, 2002, 41, 10554-10562.
  • Berezovski, M.; Li, W.-P.; Poulter, C.D.; Krylov, S. N. "Measuring the Activity of Farnesyltransferase by Capillary Electrophoresis with Laser-Induced Fluorescence Detection" Electrophoresis, 2002, 23, 3398-3403.
  • Iwata-Reuyl, D.; Math, S.K.; Poulter, C.D. "Bacterial Phytoene Synthase: Molecular Cloning, Over-Expression and Characterization of Erwinia herbicola Phytoene Synthase" Biochemistry, 2003, 42, 3359-3365.
  • Wouters, J.; Oudjama, Y.; Barkley, S.J.; Tricot, C.; Stalon, V.; Droogmans, L.; Poulter, C.D. "Catalytic Mechanism of E. coli Isopentenyl Diphosphate Isomerase Involves Cys67, Glu116 and Tyr104 as Suggested by Crystal Structures of Complexes with Transition State Analogues and Irreversible Inhibitors" J. Biol. Chem., 2003, 278, 11903-11908.
  • Eubanks, L.M.; Poulter, C.D. "Rhodobacter capsulatus 1-Deoxy-D-xylulose 5-Phosphate Synthase: Steady-State Kinetics and Substrate Binding" Biochemistry, 2003, 42, 1140-1149.
  • Hemmerlin, A.; Rivera, S.B.; Erickson, H.; Poulter, C.D. "Enzymes Encoded by the Farnesyl Diphosphate Synthase Gene Family in the Big Sagebrush Artemisia tridentata spp. spiciformis" J. Biol. Chem., 2003, 34, 32132-32140.
  • Erickson, H.; Poulter, C.D. "Chrysanthemyl Diphosphate Synthase. The Relationship among Chain Elongation, Branching and Cyclopropanation Reactions in the Isoprenoid Biosynthetic Pathway" J. Am. Chem. Soc., 2003, 23, 6885-6888.
  • Carrigan, C.N.; Poulter, C.D. "Zinc is an Essential Cofactor for Type I Isopentenyl Diphosphate: Dimethylallyl Diphosphate Isomerase" J. Am. Chem. Soc., 2003, 30, 9008-9009.
  • Barkley, S.J.; Cornish, R.M.; Poulter, C.D. "Identification of an Archaeal Type II Isopentenyl Diphosphate Isomerase in Methanothermobacter thermautotrophicus" J. Bacteriology, in press.
  • Testa, C.A.; Cornish, R.M.; Poulter, C.D. " The Sorbitol Phosphotransferase System is Responsible for the Transport of 2-C-Methyl D-Erythriotol into Salmonella enterica terovar Typhimurium" J. Bacteriology, 2004, 186, 473-480.
  • Scholte, A.; Eubanks, L.; Poulter, C.D.; Vederas, J. " Synthesis and Biological Activity of Isopentenyl Diphosphate Analogs." Bioorganic and Medical Chemistry, 2004, 12, 763-770.
  • Wouters, J; Oudjama, Y.; Stalon, V.; Droogmans, L.; Poulter, C. D. "Crystal Structure of the C67A Mutant of Isopentenyl Diphosphate Isomerase Complexed with a Mechanism-Based Irreversible Inhibitor" Proteins, 2004, 54, 216-221.
  • McDougal, O.M.; Poulter, C.D. "Three-Dimensional Structure of the Mini-M Conotoxin mr3a" Biochemistry, 2004, 43, 425-429.
  • Barkley, S.J; Desai, S. B.; Poulter, C.D. "Proton Exchange in Type II Isopentenyl Diphosphate Isomerase" Organic Letters, 2004, 6, 5019-5021.
  • Barkley, S.J.; Desai, S. B.; and Poulter, C.D. "Type II Isopentenyl Diphosphate Isomerase from Synechocystis sp. Strain PCC 6803"J. of Bacteriology, 2004, 8156-8158.
  • Fox, D.T.; Poulter, C.D. "Synthesis and Evaluation of 1-Deoxy-D-xylulose 5-Phosphoric Acid Analogs as Alternate Substrates for Methylerythritol Phosphate Synthase" J. Org. Chem., 2005, 70, 1978-1985.
  • Fox, D.T.; Poulter, C.D. "Mechanistic Studies with 2C-Methyl-D-erythritol 4-Phosphate Synthase from Escherichia coli" Biochemistry, 2005, 44, 8360-8368.
  • de Ruyck, J.; Rothman, S.C.; Poulter, C.D.; Wouters, J. "Structure of Thermus thermophilus type 2 isopentenyl diphosphates isomerase inferred from crystallography and molecular dynamics" Biochem. and Biophys. Res. Comm., 2005, 338, 1515-1518.
  • Walker, J.R.; Poulter, C.D. "Synthesis and Evaluation of 1-Deoxy-D-xylulose 5-Phosphate Analogs as Chelation Based Inhibitors of Methylerythritol Phosphate Synthase" J. Org. Chem., 2005, 70, 9955-9959.
  • Wu, Z.; Wouters, J.; Poulter, C.D. "Isopentenyl Diphosphate Isomerase. Mechanism-Based Inhibition by Diene Analogues of Isopentenyl Diphosphate and Dimethylallyl Diphosphte" J. Am. Chem. Soc., 2005, 127, 17433-17438.
  • Poulter, C.D. "Farnesyl Diphosphate Synthase. A Paradigm for Understanding Structure and Function Relationships in E-Polyprenyl Diphosphate Synthases" Phytochem. Reviews, 2006, 5, 17-26.
  • Testa, C.A.; Lherbet, C.; Pojer, F.; Noel, J.P; Poulter, C.D. "Cloning and Expression of IspDF from Mesorhizobium loti. Characterization of a Bifunctional Protein that Catalyzes Non-Consecutive Steps in the Methylerythritol Phosphate Pathway" Biochem. Biophys. Acta, 2006, 1764, 85-96.
  • Cornish, R.M.; Roth, J.R.; Poulter, C.D. "Lethal mutations in the isoprenoid pathway of Salmonella enterica" J. Bacteriol., 2006, 188, 1444-1450.
  • Lherbet, C.; Pojer, F.; Richard, S.B.; Noel, J.P.; Poulter, C.D. "Absence of Substrate Channeling between Active Sites in the Agrobacterium tumefaciens IspDF and IspE Enzymes of the Methyl Erythritol Phosphate Pathway" Biochemistry, 2006, 45, 3548-3553.
  • Thulasiram, H.V.; Phan, R.M.; Rivera, S.B.; Poulter, C.D. "Synthesis of Deuterium Labeled Derivatives of Dimethylallyl Diphosphate" J. Org. Chem., 2006, 71, 1739-1741.
  • Gauchet, C.; Labadie, G.R.; Poulter, C.D. "Regio- and Chemoselective Covalent Immobilization of Proteins through Unnatural Amino Acids" J. Am. Chem. Soc. 2006, 128, 9274-9275.
  • Lee, S.; Poulter, C.D. "Escherichia coli Type I Isopentenyl Diphosphate Isomerase: Structural and Catalytic Roles for Divalent Metals" J. Am. Chem. Soc. 2006, 128, 11545-11550.
  • Thulasiram, H.V.; Poulter, C.D. "Farnesyl Diphosphate Synthase: The Art of Compromise between Substrate Selectivity and Stereoselectivity" J. Am. Chem. Soc. 2006, 128, 15819-15823.
  • Rothman, S.C.; Poulter, C.D. "Kinetic and Spectroscopic Characterization of Type II Isopentenyl Diphosphate Isomerase from Thermus thermophilus: Evidence for Formation of Substrate-induced Flavin Species" Biochemistry, in press.
  • Thulasiram, H.V.; Erickson, H.K.; Poulter, C.D. "Chimeras of Two Isoprenoid Synthases Catalyze all Four Coupling Reactions in Isoprenoid Biosynthesis" Science 2007,316, 73-76.
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